L'application de kinesio tape à la population lombalgique chronique non spécifique: quelle est l'influence des circonvolutions sur la douleur et l'incapacité fonctionnelle ? : travail de bachelor

Introduction : La lombalgie est la problématique la plus fréquente amenant à consulter un médecin, dans le cadre de douleurs musculo-squelettiques. En effet, il s’agit de la première cause d’arrêt de travail pour les Européens agés de moins de 45 ans. Parmis ces personnes souffrant du dos, la majorité n’en souffre que de manière éphémère. Cependant, 10% d’entre elles entrent dans un schéma de chronicité. Ces douleurs prolongées dans le temps sur plusieurs mois, voire années, sont coûteuses pour la société et difficiles à gérer tant pour les patients que pour les thérapeutes. Ainsi, il paraît judicieux d’élargir la recherche quant à de nouvelles thérapies telles que le kinesio taping. Basée sur un effet réflexe provoqué par un phénomène d’ondulation sur la peau, cette méthode novatrice, réservée aux sportifs il y a encore quelques années, s’étend désormais au grand public. Objectif : L’objectif de cette revue est de démontrer l’effet réflexe sur la douleur et l’incapacité fonctionnelle des ondulations que le kinesio tape induit sur la peau en comparaison à un contrôle ne provoquant aucune circonvolution. Méthode : Grâce à l’utilisation de différentes bases de données (PubMed, PEDro, Cochrane et Embase) nous avons sélectionné trois études comparables. Originaires du Brésil pour deux d’entre elles et d’Arabie Saoudite pour la dernière, ces trois études sont des études randomisées contrôlées. Résultats : Les résultats ne sont pas similaires selon les trois études. Effectivement, si les trois obtiennent des améliorations sur la douleur et l’incapacité fonctionnelle dans chacun des groupes, une seule d’entre elles confirme notre hypothèse en obtenant des différences inter-groupe significatives en faveur du groupe expérimental utilisant un kinesio tape avec circonvolutions. Conclusion : Obtenant des résultats mitigés, cette revue n’est pas suffisante pour incriminer ou non les circonvolutions dans l’effet du kinesio tape sur la douleur et l’incapacité fonctionnelle chez les personnes souffrant de lombalgie chronique non spécifique. Tous les groupes obtenant des améliorations sur ces outcomes, il serait nécessaire d’entreprendre plus de recherches comparant le kinesio taping à aucune intervention chez cette même population

Economical Evaluation through Gross Profit and Cash Flow in Different Beef Cattle Systems in Rio Grande Do Sul

Beef cattle production is suffering numerous difficulties in productive and economical terms in the state of Rio Grande do Sul. Expanding new markets, competition with other meats, external competition through imported Mercosul beef, new growth and slaughter processes bring new challenges to the Brazilian livestock production. In the case of Rio Grande do Sul, another factor to be considered is the competition with Central States in the internal market. Meat prices received by farmers in the last years stayed constant, but prices of the main production inputs are still rising. This scenery brought continuous income decrease to the beef cattle farmers. As a result, many farmers are selling part of their lands or leaving beef cattle production. This paper aims to compare gross income and cash flows in three farms with different beef cattle systems during the years of 2003 and 2004, as well as analysing the cost percentage of different inputs necessary to the production systems. The farms are located in different regions: Campanha, Depressão Central and Fronteira Oeste, representing important agricultural production regions in the in Rio Grande do Sul state. The results show that without technological modernisation in beef cattle production systems and integration with agriculture, it becomes difficult to remunerate all the production factors. Planning allows a better income distribution, reducing the months of negative cash flow. However, the low profit per area demonstrates the gravity of the economical situation of beef cattle farmers in Rio Grande do Sul.beef cattle systems, gross profit, cash flow, Livestock Production/Industries,

Macrophage Trafficking as Key Mediator of Adenine-Induced Kidney Injury

Macrophages play a special role in the onset of several diseases, including acute and chronic kidney injuries. in this sense, tubule interstitial nephritis (TIN) represents an underestimated insult, which can be triggered by different stimuli and, in the absence of a proper regulation, can lead to fibrosis deposition. Based on this perception, we evaluated the participation of macrophage recruitment in the development of TIN. Initially, we provided adenine-enriched food to WT and searched for macrophage presence and action in the kidney. Also, a group of animals were depleted of macrophages with the clodronate liposome while receiving adenine-enriched diet. We collected blood and renal tissue from these animals and renal function, inflammation, and fibrosis were evaluated. We observed higher expression of chemokines in the kidneys of adenine-fed mice and a substantial protection when macrophages were depleted. Then, we specifically investigated the role of some key chemokines, CCR5 and CCL3, in this TIN experimental model. Interestingly, CCR5 KO and CCL3 KO animals showed less renal dysfunction and a decreased proinflammatory profile. Furthermore, in those animals, there was less profibrotic signaling. in conclusion, we can suggest that macrophage infiltration is important for the onset of renal injury in the adenine-induced TIN.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Instituto Nacional de Ciencia e Tecnologia de Fluidos Complexos (INCT Complex Fluids)Univ São Paulo, Inst Biomed Sci, Dept Immunol, Lab Transplantat Immunobiol, BR-05508900 São Paulo, BrazilUniversidade Federal de São Paulo, Div Nephrol, Lab Clin & Expt Immunol, BR-04023900 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Biophys, BR-04023062 São Paulo, BrazilUniv São Paulo, Inst Chem, Dept Biochem, BR-05508000 São Paulo, BrazilUniv São Paulo, Sch Med Ribeirao Preto, Dept Biochem & Immunol, BR-14049900 Ribeirao Preto, SP, BrazilUniversidade Federal de São Paulo, Div Nephrol, Lab Clin & Expt Immunol, BR-04023900 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Biophys, BR-04023062 São Paulo, BrazilFAPESP: 2009/54474-8FAPESP: 2012/02270-2FAPESP: 2013/25010-9Web of Scienc

Antioxidant, anti-acetylcholinesterase and cytotoxic activities of ethanol extracts of peel, pulp and seeds of exotic Brazilian fruits Antioxidant, anti-acetylcholinesterase and cytotoxic activities in fruits

Ethanol extracts of powdered genipap (Genipa americana L), umbu (Spondia tuberosa A.) and siriguela (Spondia purpurea L) prepared from separate pulp, seeds and peel were investigated for their (i) antioxidant capacity, which was evaluated by various known methods; (ii) acetylcholinesterase (AChE) inhibitory activity; and (iii) cytotoxic effect on corneal epithelial cells of sheep. the highest values of total phenolic content were obtained with peel and seed extracts. Siriguela and umbu (seeds and peel) extracts displayed the highest antioxidant activities. Lipid peroxidation assays using mimetic biomembranes and mouse liver homogenates indicated that genipap pulp is a promising antioxidant. the investigation of phenols and organic acid contents revealed the presence of quercetin, citric and quinic acids, chlorogenic acid derivatives, among others, in several extracts, with the highest amount found in siriguela seeds. Genipap pulp and siriguela seed ethanol extracts presented an AChE inhibition zone similar to that of the positive control, carbachol. AChE inhibition assay with chlorogenic acid, one of the main constituents of siriguela seeds, revealed that this acid showed activity similar to that of the control physostigmine. These data suggest that these extracts are potentially important antioxidant supplements for the everyday human diet, pharmaceutical and cosmetic industries. (C) 2012 Elsevier B.V. All rights reserved.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)INCT-RedoxomaINCT-BioanaliticaUniv Fed Alagoas, Inst Quim & Biotecnol, BR-57072970 Maceio, AL, BrazilUniv Pernambuco, BR-56300000 Petrolina, PE, BrazilUniv Fed Alagoas, Rede Nordeste Biotecnol RENORBIO, BR-57072970 Maceio, AL, BrazilUniv Fed Alagoas, Inst Ciencias Biol & Saude, BR-57072970 Maceio, AL, BrazilUniv São Paulo, Inst Quim, Dept Bioquim, BR-05508000 São Paulo, BrazilUniversidade Federal de São Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972270 Diadema, SP, BrazilUniv Estadual Campinas, Inst Biol, Dept Biol Vegetal, Campinas, SP, BrazilUniv Fed Ceara, Dept Quim Organ & Inorgan, BR-60021970 Fortaleza, CE, BrazilEmbrapa Tabuleiros Costeiros, Tabuleiro Martins, BR-57061970 Maceio, AL, BrazilUniversidade Federal de São Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-09972270 Diadema, SP, BrazilFAPESP: 2008/58035-6Web of Scienc

Fixation of the short-term central venous catheter. A comparison of two techniques

Purpose: To compare the fixation of the central venous catheter (CVC) using two suture techniques. Methods: A clinical, analytical, interventional, longitudinal, prospective, controlled, single-blind and randomized study in adult, intensive care unit (ICU) patients. After admission and indication of CVC use, the patients were allocated to the Wing group (n = 35, catheter fixation with clamping wings and retainers) or Shoelace group (n = 35, catheter fixation using shoelace cross- tied sutures around the device). Displacement, kinking, fixation failure, hyperemia at the insertion site, purulent secretion, loss of the device, psychomotor agitation, mental confusion, and bacterial growth at the insertion site were evaluated. Results: Compared with the Wing group, the Shoelace group had a lower occurrence of catheter displacement (n = 0 versus n = 4p = 0.04), kinking (n = 0 versus n = 8p = 0.001), and fixation failure (n = 2 versus n = 8p = 0.018). No significant difference was found in bacterial growth (n = 20 versus n = 14p = 0.267) between groups. Conclusion: The Shoelace fixation technique presented fewer adverse events than the Wing fixation technique.Univ Vale Sapucai UNIVAS, Profess Masters Program Appl Hlth Sci, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Profess Masters Program Appl Hlth Sci, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Hosp Clin Samuel Libanio, Dept Cardiac Surg, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Dept Biostat, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Res Lab, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Hosp Clin Samuel Libanio, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Hosp Clin Samuel Libanio, Intens Care Dept, Pouso Alegre, MG, BrazilUniv Vale Sapucai, Pouso Alegre, MG, BrazilUniv Fed São Paulo UNIFESP, Div Plast Surg, São Paulo, BrazilUniv Fed São Paulo UNIFESP, Div Plast Surg, Dept Surg, São Paulo, BrazilUniv Fed São Paulo UNIFESP, Div Plast Surg, São Paulo, BrazilUniv Fed São Paulo UNIFESP, Div Plast Surg, Dept Surg, São Paulo, BrazilWeb of Scienc

Serological evidence of hantavirus infection in rural and urban regions in the state of Amazonas, Brazil

Hantavirus disease is caused by the hantavirus, which is an RNA virus belonging to the family Bunyaviridae. Hantavirus disease is an anthropozoonotic infection transmitted through the inhalation of aerosols from the excreta of hantavirus-infected rodents. In the county of Itacoatiara in the state of Amazonas (AM), Brazil, the first human cases of hantavirus pulmonary and cardiovascular syndrome were described in July 2004. These first cases were followed by two fatal cases, one in the municipality of Maues in 2005 and another in Itacoatiara in 2007. In this study, we investigated the antibody levels to hantavirus in a population of 1,731 individuals from four different counties of AM. Sera were tested by IgG/IgM-enzyme-linked immune-sorbent assay using a recombinant nucleocapsid protein of the Araraquara hantavirus as an antigen. Ten sera were IgG positive to hantavirus (0.6%). Among the positive sera, 0.8% (1/122), 0.4% (1/256), 0.2% (1/556) and 0.9% (7/797) were from Atalaia do Norte, Careiro Castanho, Itacoatiara and Labrea, respectively. None of the sera in this survey were IgM-positive. Because these counties are distributed in different areas of AM, we can assume that infected individuals are found throughout the entire state, which suggests that hantavirus disease could be a local emerging health problem.FAPEAMFAPEAMCNPqCNPqCAPESCAPESSUFRAMASUFRAM

Drought stress and tree size determine stem CO2 efflux in a tropical forest

CO2 efflux from stems (CO2_stem) accounts for a substantial fraction of tropical forest gross primary productivity, but the climate sensitivity of this flux remains poorly understood. We present a study of tropical forest CO2_stem from 215 trees across wet and dry seasons, at the world's longest running tropical forest drought experiment site. We show a 27% increase in wet season CO2_stem in the droughted forest relative to a control forest. This was driven by increasing CO2_stem in trees 10–40 cm diameter. Furthermore, we show that drought increases the proportion of maintenance to growth respiration in trees > 20 cm diameter, including large increases in maintenance respiration in the largest droughted trees, > 40 cm diameter. However, we found no clear taxonomic influence on CO2_stem and were unable to accurately predict how drought sensitivity altered ecosystem scale CO2_stem, due to substantial uncertainty introduced by contrasting methods previously employed to scale CO2_stem fluxes. Our findings indicate that under future scenarios of elevated drought, increases in CO2_stem may augment carbon losses, weakening or potentially reversing the tropical forest carbon sink. However, due to substantial uncertainties in scaling CO2_stem fluxes, stand‐scale future estimates of changes in stem CO2 emissions remain highly uncertain.This work is a product of a UK NERC independent fellowship grant NE/N014022/1 to L.R., a UK NERC grant NE/J011002/1 to P.M. and M.M., CNPQ grant 457914/2013-0/MCTI/CNPq/FNDCT/LBA/ESECAFLOR to A.C.L.d.C., an ARC grant FT110100457 to P.M. It was previously supported by NERC NER/A/S/2002/00487, NERC GR3/11706, EU FP5-Carbonsink and EU FP7-Amazalert to P.M

Broadened T-cell Repertoire Diversity in ivIg-treated SLE Patients is Also Related to the Individual Status of Regulatory T-cells

Intravenous IgG (ivIg) is a therapeutic alternative for lupus erythematosus, the mechanism of which remains to be fully understood. Here we investigated whether ivIg affects two established sub-phenotypes of SLE, namely relative oligoclonality of circulating T-cells and reduced activity of CD4 + Foxp3+ regulatory T-cells (Tregs) reflected by lower CD25 surface density.Octapharma research funding; Fundação para a Ciência e a Tecnologia postdoctoral fellowships: (SFRH/BPD/20806/2004, SFRH/BPD/34648/2007); FCT Programa Pessoa travel grant